Making “Sense” of Genetics Today – Karl Chai

• This book returns the Law of Genetics to its simple core in the original discovery and in the applications to genetic studies over the past 120 years, as well as that of today.
• Using classic human hereditary disorders as examples, such as alkaptonuria, sickle cell anemia, Huntington Disease, and cystic fibrosis, the methods of determining the molecular genetic basis of such diseases are outlined.
• The genetics principle at play behind the modern-day “genome-wide association studies” and the variations on the theme is explained for a more sensible and careful evaluation of the findings.
• It provides an overview on some state-of-the-art applications of genetics in modern medicine, and an outlook on the tasks ahead and benefits to expect for mankind.

• The book is appropriate for interested readers ranging from students taking genetics courses in high school or college, to scientists and clinicians making sense of the findings from genetic studies.